Selected Publications

2023

Shah K, He S, Turner DJ, Corbo J, Rebbani K, Bateman JM, Cheloufi S, Igreja C, Valkov E, Murn J. A paradigm for regulation at the effector interface with RNA-binding proteins. PMID: 37790431 bioRxiv [Preprint], 2023 available from: https://doi.org/10.1101/2023.09.20.558714 (Under review)

2022

He S, Valkov E, Cheloufi S, Murn J (2022) The nexus of RNA-binding proteins and their effectors Nat Rev Genet. doi: 10.1038/s41576-022-00550-0

Hsu PP, Do BT, Vermeulen SY, Wang Z, Hirz T, Aziz N, Replogle JM, Abbott KL, Block S, Darnell AM, Ferreira R, Milosevic JT, Schmidt DR, Chidley C, Su XA, Harris IS, Weissman JS, Cheloufi S, Sykes DB & Vander Heiden MG. Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress. BioRxiv 503984 [Preprint], August 16, 2022. Available from: https://doi.org/10.1101/2022.08.16.503984

Franklin R, Guo Y, He S, Ji F, Chen M, Zhou X, Frankhouser D, Do BT, Chiem C, Jang M, Blanco A, Vander Heiden MG, Rockne RC, Ninova M, Sykes DB, Hochedlinger K, Lu R, Sadreyev R, Murn J, Volk A, Cheloufi1 S.(2022) Regulation of chromatin accessibility by the Histone Chaperone CAF-1 sustains lineage fidelity. Nat Commun. doi: 10.1038/s41467-022-29730-6

2021

M. Andrés Blanco, David B. Sykes, Lei Gu, Mengjun Wu, Ricardo Petroni, Rahul Karnik, Mathias Wawer, Joshua Rico, Haitao Li, William D. Jacobus, Ashwini Jambhekar, Sihem Cheloufi, Alexander Meissner, Konrad Hochedlinger, David T. Scadden, Yang Shi. Chromatin state barriers enforce an irreversible mammalian cell fate decision. Cell Reports doi: 10.1016/j.celrep.2021.109967

Franklin R, Murn J and Cheloufi S (2021) Cell Fate Decisions in the Wake of Histone H3 Deposition. Front. Cell Dev. Biol. 9:654915.

doi: 10.3389/fcell.2021.654915

Shi, J., Y. Zhang, D. Tan, X. Zhang, M. Yan, Y. Zhang, R. Franklin, M. Shahbazi, K. Mackinlay, S. Liu, B. Kuhle, E. R. James, L. Zhang, Y. Qu, Q. Zhai, W. Zhao, L. Zhao, C. Zhou, W. Gu, J. Murn, J. Guo, D. T. Carrell, Y. Wang, X. Chen, B. R. Cairns, X. L. Yang, P. Schimmel, M. Zernicka-Goetz, S. Cheloufi, Y. Zhang, T. Zhou, and Q. Chen. Pandora-Seq Expands the Repertoire of Regulatory Small RNAs by Overcoming RNA Modifications. Nat Cell Biol (Apr 5 2021).

doi: 10.1038/s41556-021-00652-7

2020

Guo, Y., Ji, F., Murn, J., Frankhouser. D., Blanco, M.A., Chiem, C., Jang, M., Sadreyev, R., Rockne, R.C., Sykes, D. B., Hochedlinger, K., Cheloufi, S. (2020). CAF-1 Histone Chaperone is a Repressor of Mixed Lineages in Myeloid Progenitors. BioRxiv [Preprint]

10.1101/2020.10.22.350447

2018

Schwarz, B. A., M. Cetinbas, K. Clement, R. M. Walsh, S. Cheloufi, H. Gu, J. Langkabel, et al. "Prospective Isolation of Poised Ipsc Intermediates Reveals Principles of Cellular Reprogramming." Cell Stem Cell 23, no. 2 (Aug 2 2018): 289-305 e5. https://doi.org/10.1016/j.stem.2018.06.013

2017

Cheloufi, S., and K. Hochedlinger. "Emerging Roles of the Histone Chaperone Caf-1 in Cellular Plasticity." Curr Opin Genet Dev 46 (Oct 2017): 83-94.

https://doi.org/10.1016/j.gde.2017.06.004

2016

Borkent, M., B. D. Bennett, B. Lackford, O. Bar-Nur, J. Brumbaugh, L. Wang, Y. Du, et al. "A Serial Shrna Screen for Roadblocks to Reprogramming Identifies the Protein Modifier Sumo2." Stem Cell Reports 6, no. 5 (May 10 2016): 704-16. https://doi.org/10.1016/j.stemcr.2016.02.004

https://www.ncbi.nlm.nih.gov/pubmed/26947976

Li, Y., M. Basavappa, J. Lu, S. Dong, D. A. Cronkite, J. T. Prior, H. C. Reinecker, et al. "Induction and Suppression of Antiviral Rna Interference by Influenza a Virus in Mammalian Cells."

Nat Microbiol 2 (Dec 5 2016): 16250.

https://doi.org/10.1038/nmicrobiol.2016.250

2015

Cheloufi, S., U. Elling, B. Hopfgartner, Y. L. Jung, J. Murn, M. Ninova, M. Hubmann, et al. "The Histone Chaperone Caf-1 Safeguards Somatic Cell Identity." Nature 528, no. 7581 (Dec 10 2015): 218-24.

https://doi.org/10.1038/nature15749

Murn, J., K. Zarnack, Y. J. Yang, O. Durak, E. A. Murphy, S. Cheloufi, D. M. Gonzalez, et al. "Control of a Neuronal Morphology Program by an Rna-Binding Zinc Finger Protein, Unkempt." Genes Dev 29, no. 5 (Mar 1 2015): 501-12.

https://doi.org/10.1101/gad.258483.115

2012

Van Stry, M., T. H. Oguin, 3rd, S. Cheloufi, P. Vogel, M. Watanabe, M. R. Pillai, P. Dash, et al. "Enhanced Susceptibility of Ago1/3 Double-Null Mice to Influenza a Virus Infection." J Virol 86, no. 8 (Apr 2012): 4151-7.

https://doi.org/10.1128/JVI.05303-11

Cheloufi, S., and K. Hochedlinger."Reproductive Biology: Stem Cells Bear Eggs." Nature 491, no. 7425 (Nov 22 2012): 535-6. https://doi.org/10.1038/491535a

2010

Cheloufi, S., C. O. Dos Santos, M. M. Chong, and G. J. Hannon. "A Dicer-Independent Mirna Biogenesis Pathway That Requires Ago Catalysis." Nature 465, no. 7298 (Jun 3 2010): 584-9. https://doi.org/10.1038/nature09092. https://www.ncbi.nlm.nih.gov/pubmed/20424607

Karginov, F. V., S. Cheloufi, M. M. Chong, A. Stark, A. D. Smith, and G. J. Hannon. "Diverse Endonucleolytic Cleavage Sites in the Mammalian Transcriptome Depend Upon Micrornas, Drosha, and Additional Nucleases." Mol Cell 38, no. 6 (Jun 25 2010): 781-8. https://doi.org/10.1016/j.molcel.2010.06.001

Chong, M. M., G. Zhang, S. Cheloufi, T. A. Neubert, G. J. Hannon, and D. R. Littman. "Canonical and Alternate Functions of the Microrna Biogenesis Machinery." Genes Dev 24, no. 17 (Sep 1 2010): 1951-60.

https://doi.org/10.1101/gad.1953310

For a complete list of publications go HERE