Welcome to the CHELOUFI LAB
The Cheloufi lab brings together expertise in stem cell, RNA and chromatin research to understand the mechanisms of cellular plasticity with the broader vision to apply our findings in therapeutic settings. My research group is leveraging molecular biology, systems biology and biochemical approaches to understand the role of chromatin and regulatory RNAs in mammalian cell fate decisions. In particular, we have been focusing on histone chaperone and tRNA processing pathways. Guided by our expertise and findings, we have recently expanded our work to investigate the regulation and function of transposable elements in cellular plasticity.